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Article 67(5); May 2024
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Influence of infant microbiome on health and development
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<dd style="color: #6f6f6f;">
Noelle Younge
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Clin Exp Pediatr.
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2024;67(5):224-231. Published online August 21, 2023
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· The infant gut microbiome is highly dynamic and individualized.
<br>
· Microbes are vertically transmitted from mother to infant during delivery and throughout infancy.
<br>
· Delivery mode, gestational age, diet, and antibiotic use influence infant microbiome composition and function.
<br>
· In animal studies, the microbiome played critical roles in the structural and functional development of the infant gastrointestinal and immune systems.
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· Microbiome-targeted therapies have great potential to reduce infant morbidity and mortality.
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Childrenâs health affected by parentâs behavioral characteristics: a review
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<dd style="color: #6f6f6f;">
Sung Eun Kim, Jongin Lee
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Clin Exp Pediatr.
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2024;67(5):232-239. Published online August 21, 2023
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· Parentsâ occupational hazards, long working hours, and smoking behaviors should be modified adequately to minimize adverse health effects on their children.
<br>
· As of 2023, several diseases from fetal exposure to occupational hazards can be compensated with Industrial Accident Compensation Insurance in South Korea.
<br>
· A directed acyclic graph is recommended for medical research to control the effects of parentsâ behaviors on childrenâs health.
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Neonatology (Perinatology)
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<a href="/journal/view.php?number=20125555647">
<span class="list_title">
Updates in neonatal resuscitation: routine use of laryngeal masks as an alternative to face masks
</span>
</a>
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<dd style="color: #6f6f6f;">
Eun Song Song, Ga Won Jeon
</dd>
<dd style="font-size:14px;color:#6f6f6f;position: relative;">
<em>
Clin Exp Pediatr.
</em>
2024;67(5):240-246. Published online July 11, 2023
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</td>
<td style="padding:0px 15px;" valign="top">
In neonatal resuscitation:
<br>
· Laryngeal masks are recommended when endotracheal intubation or positive-pressure ventilation fails.
<br>
· Laryngeal masks are useful even during chest compressions.
<br>
· Laryngeal masks aid neonates >34 weeksâ gestation and/or with a birth weight >2 kg.
<br>
· Main usage barriers include limited experience (81%), preference for endotracheal tubes (57%), and lack of awareness (56%).
<br>
· Second-generation laryngeal masks have a built-in esophageal drainage tube that prevents regurgitation into the glottis, and an orogastric tube can be inserted within the esophageal drainage tube to protect against gastric inflation.
</td>
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<div style="position: relative;">
DOI:
<a href="https://doi.org/10.3345/cep.2023.00619">
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https://doi.org/10.3345/cep.2023.00619
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Neonatology (Perinatology)
</dd>
<dd style="margin-bottom:7px;">
<a href="/journal/view.php?number=20125555673">
<span class="list_title">
Exploring the role of laryngeal masks in neonatal resuscitation
</span>
</a>
</dd>
<dd style="color: #6f6f6f;">
Euiseok Jung
</dd>
<dd style="font-size:14px;color:#6f6f6f;position: relative;">
<em>
Clin Exp Pediatr.
</em>
2024;67(5):247-248. Published online December 28, 2023
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<td style="padding:0px 15px;" valign="top">
· Laryngeal masks (LMs) offer stable airway access and skill retention advantages, making them promising alternatives to positive-pressure ventilation in neonatal care.
<br>
· The ease of teaching LM insertion techniques to less experienced providers addresses the need for swift intervention and skill retention.
<br>
· Careful consideration of the benefits and challenges of LMs is essential in determining their effective integration into enhanced neonatal resuscitation protocols.
</td>
</tr>
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DOI:
<a href="https://doi.org/10.3345/cep.2023.01200">
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Neonatology (Perinatology)
</dd>
<dd style="margin-bottom:7px;">
<a href="/journal/view.php?number=20125555686">
<span class="list_title">
Effect of vitamin E supplementation on bilirubin levels in infants with hyperbilirubinemia: a double-blind randomized clinical trial
</span>
</a>
</dd>
<dd style="color: #6f6f6f;">
Mojtaba Cheraghi, Maziar Nikouei, Majid Mansouri, Siros Hemmatpour, Yousef Moradi
</dd>
<dd style="font-size:14px;color:#6f6f6f;position: relative;">
<em>
Clin Exp Pediatr.
</em>
2024;67(5):249-256. Published online March 26, 2024
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<td style="padding:0px 15px;" valign="top">
<b>
Question:
</b>
Is vitamin E a viable therapeutic option for managing neonatal hyperbilirubinemia?
<br>
<b>
Finding:
</b>
This randomized clinical trial examined the effects of oral vitamin E supplementation on bilirubin reduction (primary outcome), phototherapy duration, and length of hospital stay (secondary outcome) in 138 infants.
<br>
<b>
Meaning:
</b>
Infants administered vitamin E versus placebo demonstrated similar reductions in bilirubin levels and length of hospital stay.
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<a href="https://doi.org/10.3345/cep.2023.01312">
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https://doi.org/10.3345/cep.2023.01312
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Pulmonology
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<a href="/journal/view.php?number=20125555688">
<span class="list_title">
Oligohydramnios affects pulmonary functional/structural abnormalities in school-aged children with bronchopulmonary dysplasia
</span>
</a>
</dd>
<dd style="color: #6f6f6f;">
Jeong Eun Shin, Soon Min Lee, Mi-Jung Lee, Jungho Han, Joohee Lim, Haerin Jang, Ho Seon Eun, Min Soo Park, Soo Yeon Kim, Myung Hyun Sohn, Ji Ye Jung, Kyung Won Kim
</dd>
<dd style="font-size:14px;color:#6f6f6f;position: relative;">
<em>
Clin Exp Pediatr.
</em>
2024;67(5):257-266. Published online April 16, 2024
</dd>
<dd style="padding:10px 0px;">
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<img class="thumb" onclick="openPhotoView(this,'cep-2023-01053.xml','cep-2023-01053f4.jpg')" src="/upload/thumbnails/cep-2023-01053f4.jpg" style="padding:2px;width:320px;cursor:pointer;">
</td>
<td style="padding:0px 15px;" valign="top">
<b>
Question:
</b>
Is bronchopulmonary dysplasia (BPD) associated with functional/structural abnormalities later in life?
<br>
<b>
Finding:
</b>
School-aged children with severe BPD had abnormalities on pulmonary function tests and lung computed tomography despite no subjective respiratory symptoms; however, only prenatal oligohydramnios and prolonged ventilator use were associated with abnormal lung function.
<br>
<b>
Meaning:
</b>
Long-term monitoring of preterm infantsâ lung health is essential, especially for those with prenatal oligohydramnios or prolonged ventilator use.
</td>
</tr>
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DOI:
<a href="https://doi.org/10.3345/cep.2023.01053">
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https://doi.org/10.3345/cep.2023.01053
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